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88 kg, or 2 pounds, on average, over a period of several weeks (13). Their conclusion sums it up quite nicely: …Garcinia extractsHCA can cause short-term weight loss. The magnitude of the effect is small, and the clinical relevance is uncertain. I agree. It may cause a mild effect in some people, but overall the effects are small and unlikely to make a major difference Bottom Line: There have been many studies conducted on Garcinia Cambogia in overweight individuals.